DOSE-DEPENDENT INTERACTION OF PARASITES WITH TIERS OF HOST DEFENSE PREDICTS "WORMHOLES" THAT PROLONG INFECTION AT INTERMEDIATE INOCULUM SIZES.

Dose-dependent interaction of parasites with tiers of host defense predicts "wormholes" that prolong infection at intermediate inoculum sizes.

Immune responses are induced by parasite exposure and can in turn reduce parasite burden.Despite such apparently simple rules of engagement, key drivers of within-host dynamics, including dose-dependence of defense and infection duration, have proven difficult to predict.Here, we model how varied inoculating doses interact with multi-tiered host de

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High energy particle collisions near black holes

If two geodesic particles collide near a rotating black hole, their energy in the centre of mass frame Ec.m.can become unbound under certain conditions (the so-called BSW effect).The special Pump Mounting Brackets role is played here by so-called critical geodesics when one of particles has fine-tuned energy and angular momentum.The nature of geode

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3D Simplification Methods and Large Scale Terrain Tiling

This paper tackles the problem of generating world-scale multi-resolution triangulated irregular networks optimized for web-based visualization.Starting with a large-scale high-resolution regularly gridded terrain, we create a pyramid of triangulated irregular networks representing distinct levels of detail, where each level Dispensers of detail is

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Changes in both trans- and cis-regulatory elements mediate insecticide resistance in a lepidopteron pest, Spodoptera exigua.

The evolution of insect resistance to insecticides is frequently associated with overexpression of one or more cytochrome KRILL OIL 1000MG P450 enzyme genes.Although overexpression of CYP450 genes is a well-known mechanism of insecticide resistance, the underlying regulatory mechanisms are poorly understood.Here we uncovered the mechanisms of overe

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